ChemicalNatural Sciences

Application of Computational Thermodynamics and Algorithm Development in Biotechnology

Professor Introduction

 T. Z | Ph.D. in Chemical and Molecular Engineering

Home Institute:Johns Hopkins University

[ Research Interests ] Algorithm development and design、Chemical engineering and thermodynamics programming、Machine learning and deep learning、Applications of pharmacokinetics and drug metabolism programming in biomedical engineering
[ Additional Experience ] Honorary member of the Advanced Mammalian Bio-manufacturing Innovation Center, USA;Collaborated with over thirty major pharmaceutical companies in the USA during Ph.D. studies;Developed the world's first software for predicting drug production solutions, widely used in pharmaceutical R&D and analysis
[ Publications ] Published articles on algorithm development in chemical engineering and drug development analysis

Project Description

This project focuses on leveraging mathematical and thermodynamic principles to design algorithms that optimize and solve problems in biotechnological applications within the pharmaceutical industry. Using Python and MATLAB, we will develop algorithms, perform simulations, and conduct regression analysis. The goal is to identify the most crucial algorithms for biopharmaceutical development through predictive modeling and apply these results to optimize pharmaceutical production capacity.

Project Keywords

Project Outline

Part 1 :   Introduction to Computational Thermodynamics and Biotechnology
• Overview of computational thermodynamics and its relevance to biotechnology
• Introduction to key concepts in thermodynamics and their applications in biological systems
• Discussion on the importance of algorithm development in optimizing biotechnological processes


Part 2 : Algorithm Development and Simulation
• Introduction to Python and MATLAB for algorithm development
• Design and development of algorithms based on thermodynamic principles
• Simulation of biotechnological processes using developed algorithms
• Regression analysis to validate and refine algorithms


Part 3 :  Predictive Modeling in Biopharmaceutical Development
• Development of predictive models to forecast outcomes in biopharmaceutical processes
• Identification of key algorithms that influence biopharmaceutical development
• Application of predictive models to optimize production processes in pharmaceutical companies

Part 4: Case Studies and Practical Applications
• Presentation of case studies demonstrating successful algorithm applications in biopharmaceutical development
• Analysis of real-world data from pharmaceutical companies to validate model predictions
• Discussion on the practical challenges and solutions in applying computational thermodynamics to biotechnology


Part 5 : Optimization of Pharmaceutical Production Capacity
• Strategies for leveraging predictive models to enhance production efficiency
• Application of optimized algorithms to real-world pharmaceutical production scenarios
• Evaluation of the impact of optimized algorithms on production capacity and cost-effectiveness

Part 6: Future Directions and Innovations
• Exploration of emerging trends in computational thermodynamics and biotechnology
• Discussion on potential future applications of developed algorithms in other areas of biotechnology
• Identification of new research opportunities and potential collaborations

Suitable for

High School Students : Interested in computational chemistry, thermodynamics, and biotechnological applications